Head Space Manual Static

Static Head Space Gas chromatography is a technique used for concentration and analysis of volatile organic compounds. It is an automated version of the equipment specified, for analysis of organic volatile impurities by USP <467> method IV.

A head space sample is normally prepared in a vial containing sample, a dilution solvent, a matrix modifier, and the headspace. Volatile components from complex sample mixtures can be extracted from non-volatile sample components and isolated in the headspace or vapor portion of the sample vial. An aliquot of the vapor in the headspace is then delivered to GC system to achieve the separation of all the volatile components.